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An-Chi Tien, PhD, is an assistant professor in the Department of Translational Neuroscience at Barrow Neurological Institute. He works in the Ivy Brain Tumor Center.
Dr. Tien’s expertise includes developmental biology and genetics, particularly applied to neuro-oncology. Dr. Tien is a member of the American Brain Tumor Association Alumni Research Network, the American Society of Clinical Oncology, and the Society for Neuro-Oncology.
Dr. Tien earned his doctorate degree in developmental biology from the Baylor College of Medicine in Houston. He completed his postdoctoral research fellowship at University of California San Francisco’s Institute for Regenerative Medicine.
Dr. Tien’s research focuses on establishing and optimizing pharmacodynamic tests to support clinical trials for patients with brain tumors and to better understand tumor resistance mechanisms.
- Postdoctoral Research Fellowship, University of California San Francisco, Institute for Regenerative Medicine, 2009-2016
- PhD, Baylor College of Medicine, Developmental Biology, 2009
- BS, National Taiwan University, Zoology, 2002
- American Brain Tumor Association Alumni Research Network
- American Society of Clinical Oncology
- Society for Neuro-Oncology
- Postdoctoral Fellowship, American Brain Tumor Association, 2012-2014
- Travel Award, Keystone Symposia on Molecular and Cellular Biology, Development and Cancer, 2008
TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila
Date: 09/2021
Authors: Lindsey D. Goodman, Heidi Cope, Zelha Nil, Thomas A. Ravenscroft, Wu-Lin Charng, Shenzhao Lu, An-Chi Tien, Rolph Pfundt, David A. Koolen, Charlotte A. Haaxma, Hermine E. Veenstra-Knol, Jolien S. Wassink-Ruiter, Marijke R. Wevers, Melissa Jones, Laurence E. Walsh, Victoria H. Klee, Miel Theunis, Eric Legius, Dora Steel, Katy E. Barwick, Manju A. Kurian, Shekeeb S. Mohammad, Russell C. Dale, Paulien A. Terhal, Ellen van Binsbergen, Brian Kirmse, Bethany Robinette, Benjamin Cogné, Bertrand Isidor, Theresa A. Grebe, Peggy Kulch, Bryan E. Hainline
Quantitative protein expression of blood-brain barrier transporters in the vasculature of brain metastases of patients with lung and breast cancer
Date: 07/2021
Authors: Xun Bao, Jianmei Wu, Jun Jiang, An-Chi Tien, Nader Sanai, Jing Li
A phase 0 trial of ribociclib in recurrent glioblastoma patients incorporating a tumor pharmacodynamic- And pharmacokinetic-guided expansion cohort
Date: 10/2019
Authors: An Chi Tien, Jing Li, Xun Bao, Alanna Derogatis, Seongho Kim, Shwetal Mehta, Nader Sanai
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
Date: 05/2018
Authors: Amelie Griveau, Giorgio Seano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K. Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L. Suvà, Joanna J. Phillips, Manish K. Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch
A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2
Date: 03/2017
Authors: Jing Zhou, An-Chi Tien, John A. Alberta, Scott B. Ficarro, Amelie Griveau, Yu Sun, Janhavee S. Deshpande, Joseph D. Card, Meghan Morgan-Smith, Wojciech Michowski, Rintaro Hashizume, C David James, Keith L. Ligon, William D. Snider, Peter Sicinski, Jarrod A. Marto, David H. Rowitch, Charles D. Stiles
An-Chi Tien, PhD, is an assistant professor in the Department of Translational Neuroscience at Barrow Neurological Institute. He works in the Ivy Brain Tumor Center.
Dr. Tien’s expertise includes developmental biology and genetics, particularly applied to neuro-oncology. Dr. Tien is a member of the American Brain Tumor Association Alumni Research Network, the American Society of Clinical Oncology, and the Society for Neuro-Oncology.
Dr. Tien earned his doctorate degree in developmental biology from the Baylor College of Medicine in Houston. He completed his postdoctoral research fellowship at University of California San Francisco’s Institute for Regenerative Medicine.
Dr. Tien’s research focuses on establishing and optimizing pharmacodynamic tests to support clinical trials for patients with brain tumors and to better understand tumor resistance mechanisms.
- Postdoctoral Research Fellowship, University of California San Francisco, Institute for Regenerative Medicine, 2009-2016
- PhD, Baylor College of Medicine, Developmental Biology, 2009
- BS, National Taiwan University, Zoology, 2002
- American Brain Tumor Association Alumni Research Network
- American Society of Clinical Oncology
- Society for Neuro-Oncology
- Postdoctoral Fellowship, American Brain Tumor Association, 2012-2014
- Travel Award, Keystone Symposia on Molecular and Cellular Biology, Development and Cancer, 2008
TNPO2 variants associate with human developmental delays, neurologic deficits, and dysmorphic features and alter TNPO2 activity in Drosophila
Date: 09/2021
Authors: Lindsey D. Goodman, Heidi Cope, Zelha Nil, Thomas A. Ravenscroft, Wu-Lin Charng, Shenzhao Lu, An-Chi Tien, Rolph Pfundt, David A. Koolen, Charlotte A. Haaxma, Hermine E. Veenstra-Knol, Jolien S. Wassink-Ruiter, Marijke R. Wevers, Melissa Jones, Laurence E. Walsh, Victoria H. Klee, Miel Theunis, Eric Legius, Dora Steel, Katy E. Barwick, Manju A. Kurian, Shekeeb S. Mohammad, Russell C. Dale, Paulien A. Terhal, Ellen van Binsbergen, Brian Kirmse, Bethany Robinette, Benjamin Cogné, Bertrand Isidor, Theresa A. Grebe, Peggy Kulch, Bryan E. Hainline
Quantitative protein expression of blood-brain barrier transporters in the vasculature of brain metastases of patients with lung and breast cancer
Date: 07/2021
Authors: Xun Bao, Jianmei Wu, Jun Jiang, An-Chi Tien, Nader Sanai, Jing Li
A phase 0 trial of ribociclib in recurrent glioblastoma patients incorporating a tumor pharmacodynamic- And pharmacokinetic-guided expansion cohort
Date: 10/2019
Authors: An Chi Tien, Jing Li, Xun Bao, Alanna Derogatis, Seongho Kim, Shwetal Mehta, Nader Sanai
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
Date: 05/2018
Authors: Amelie Griveau, Giorgio Seano, Samuel J. Shelton, Robert Kupp, Arman Jahangiri, Kirsten Obernier, Shanmugarajan Krishnan, Olle R. Lindberg, Tracy J. Yuen, An-Chi Tien, Jennifer K. Sabo, Nancy Wang, Ivy Chen, Jonas Kloepper, Louis Larrouquere, Mitrajit Ghosh, Itay Tirosh, Emmanuelle Huillard, Arturo Alvarez-Buylla, Michael C. Oldham, Anders I. Persson, William A. Weiss, Tracy T. Batchelor, Anat Stemmer-Rachamimov, Mario L. Suvà, Joanna J. Phillips, Manish K. Aghi, Shwetal Mehta, Rakesh K. Jain, David H. Rowitch
A Sequentially Priming Phosphorylation Cascade Activates the Gliomagenic Transcription Factor Olig2
Date: 03/2017
Authors: Jing Zhou, An-Chi Tien, John A. Alberta, Scott B. Ficarro, Amelie Griveau, Yu Sun, Janhavee S. Deshpande, Joseph D. Card, Meghan Morgan-Smith, Wojciech Michowski, Rintaro Hashizume, C David James, Keith L. Ligon, William D. Snider, Peter Sicinski, Jarrod A. Marto, David H. Rowitch, Charles D. Stiles