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Rita Sattler, PhD, is the David and Weezie Reese Chair for Neurodegeneration Research and a professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Sattler received her master’s and doctorate degrees in neurophysiology from the University of Toronto in Toronto, Canada. She completed a postdoctoral fellowship in the Department of Neuroscience at Johns Hopkins University Medical School in Baltimore, Maryland. Dr. Sattler stayed at Johns Hopkins University and attained the academic rank of assistant professor of Neurology, with a secondary appointment in the Brain Science Institute at the Johns Hopkins University School of Medicine.
Dr. Sattler is a member of the American Society for Neuroscience and the American Society for Neurochemistry. She is the recipient of several awards and fellowships, including the Governor’s Gold Medal for the highest academic achievement in graduate studies at the University of Toronto, a Human Frontier Science Program Long-term Fellowship, and a Howard Hughes Postdoctoral Fellowship. She currently serves as grant reviewer for several national and international disease foundations as well as the NIH.
Dr. Sattler’s research focuses on studies of synaptic biology in health and disease. She employs human patient-derived induced pluripotent stem cells to elucidate the mechanisms of neuronal cell death in numerous neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Dr. Sattler is principal investigator and co-investigator of numerous active grants from the NIH/NINDS as well as several disease foundations, including the ALS Association (ALSA), the Muscular Dystrophy Association (MDA) and the Robert Packard Center for ALS Research.
- Postdoctoral Fellowship, Johns Hopkins University, Department of Neuroscience, 1999-2004
- PhD, University of Toronto, Physiology, 1999
- MS, University of Toronto, Physiology, 1996
- BS, Technical University of Mannheim, Chemical and Biotechnology Engineering, 1993
- Society for Neuroscience
- American Society for Neurochemistry
- Volunteer of the year, The Robert Packard Center for ALS Research at Johns Hopkins, 2010
- Postdoctoral Fellowship, Howard Hughes Medical Institute, 2003-2004
- Governor General’s Gold Medal for the Highest Academic Achievement in Graduate Studies, University of Toronto, Toronto, Canada, 2000
- Long Term Fellowship, Human Frontier Science Program, 2000-2003
Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits
Date: 10/2023
Authors: R Keating Godfrey, Eric Alsop, Reed T. Bjork, Brijesh S. Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Lauren M. Gittings, Allison F. Michael, Christi Williams, Grace Hala'ufia, Alexander D. Blythe, Megan Hall, Rita Sattler, Kendall Van Keuren-Jensen, Daniela C. Zarnescu
Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum
Date: 09/2023
Authors: Lauren M. Gittings, Eric B. Alsop, Jerry Antone, Mo Singer, Timothy G. Whitsett, Rita Sattler, Kendall Van Keuren-Jensen
Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
Date: 01/2023
Authors: Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Editorial: Mechanisms of Action in Neurodegenerative Proteinopathies
Date: 01/2022
Authors: Sean J. Miller, Selina Wray, Rita Sattler, Can Zhang
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
Date: 07/2021
Authors: Deepti Lall, Ileana Lorenzini, Thomas A. Mota, Shaughn Bell, Thomas E. Mahan, Jason D. Ulrich, Hayk Davtyan, Jessica E. Rexach, A K. Muhammad, Oksana Shelest, Jesse Landeros, Michael Vazquez, Junwon Kim, Layla Ghaffari, Jacqueline Gire O'Rourke, Daniel H. Geschwind, Mathew Blurton-Jones, David M. Holtzman, Rita Sattler, Robert H. Baloh
- English
Rita Sattler, PhD, is the David and Weezie Reese Chair for Neurodegeneration Research and a professor in the Department of Translational Neuroscience at Barrow Neurological Institute.
Dr. Sattler received her master’s and doctorate degrees in neurophysiology from the University of Toronto in Toronto, Canada. She completed a postdoctoral fellowship in the Department of Neuroscience at Johns Hopkins University Medical School in Baltimore, Maryland. Dr. Sattler stayed at Johns Hopkins University and attained the academic rank of assistant professor of Neurology, with a secondary appointment in the Brain Science Institute at the Johns Hopkins University School of Medicine.
Dr. Sattler is a member of the American Society for Neuroscience and the American Society for Neurochemistry. She is the recipient of several awards and fellowships, including the Governor’s Gold Medal for the highest academic achievement in graduate studies at the University of Toronto, a Human Frontier Science Program Long-term Fellowship, and a Howard Hughes Postdoctoral Fellowship. She currently serves as grant reviewer for several national and international disease foundations as well as the NIH.
Dr. Sattler’s research focuses on studies of synaptic biology in health and disease. She employs human patient-derived induced pluripotent stem cells to elucidate the mechanisms of neuronal cell death in numerous neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
Dr. Sattler is principal investigator and co-investigator of numerous active grants from the NIH/NINDS as well as several disease foundations, including the ALS Association (ALSA), the Muscular Dystrophy Association (MDA) and the Robert Packard Center for ALS Research.
- Postdoctoral Fellowship, Johns Hopkins University, Department of Neuroscience, 1999-2004
- PhD, University of Toronto, Physiology, 1999
- MS, University of Toronto, Physiology, 1996
- BS, Technical University of Mannheim, Chemical and Biotechnology Engineering, 1993
- Society for Neuroscience
- American Society for Neurochemistry
- Volunteer of the year, The Robert Packard Center for ALS Research at Johns Hopkins, 2010
- Postdoctoral Fellowship, Howard Hughes Medical Institute, 2003-2004
- Governor General’s Gold Medal for the Highest Academic Achievement in Graduate Studies, University of Toronto, Toronto, Canada, 2000
- Long Term Fellowship, Human Frontier Science Program, 2000-2003
Modelling TDP-43 proteinopathy in Drosophila uncovers shared and neuron-specific targets across ALS and FTD relevant circuits
Date: 10/2023
Authors: R Keating Godfrey, Eric Alsop, Reed T. Bjork, Brijesh S. Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Lauren M. Gittings, Allison F. Michael, Christi Williams, Grace Hala'ufia, Alexander D. Blythe, Megan Hall, Rita Sattler, Kendall Van Keuren-Jensen, Daniela C. Zarnescu
Cryptic exon detection and transcriptomic changes revealed in single-nuclei RNA sequencing of C9ORF72 patients spanning the ALS-FTD spectrum
Date: 09/2023
Authors: Lauren M. Gittings, Eric B. Alsop, Jerry Antone, Mo Singer, Timothy G. Whitsett, Rita Sattler, Kendall Van Keuren-Jensen
Moderate intrinsic phenotypic alterations in ALS/FTD iPSC-microglia despite the presence of C9orf72 pathological features
Date: 01/2023
Authors: Ileana Lorenzini, Eric Alsop, Jennifer Levy, Lauren M. Gittings, Deepti Lall, Benjamin E. Rabichow, Stephen Moore, Ryan Pevey, Lynette M. Bustos, Camelia Burciu, Divya Bhatia, Mo Singer, Justin Saul, Amanda McQuade, Makis Tzioras, Thomas A. Mota, Amber Logemann, Jamie Rose, Sandra Almeida, Fen-Biao Gao, Michael Marks, Christopher J. Donnelly, Elizabeth Hutchins, Shu-Ting Hung, Justin Ichida, Robert Bowser, Tara Spires-Jones, Mathew Blurton-Jones, Tania F. Gendron, Robert H. Baloh, Kendall Van Keuren-Jensen, Rita Sattler
Editorial: Mechanisms of Action in Neurodegenerative Proteinopathies
Date: 01/2022
Authors: Sean J. Miller, Selina Wray, Rita Sattler, Can Zhang
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
Date: 07/2021
Authors: Deepti Lall, Ileana Lorenzini, Thomas A. Mota, Shaughn Bell, Thomas E. Mahan, Jason D. Ulrich, Hayk Davtyan, Jessica E. Rexach, A K. Muhammad, Oksana Shelest, Jesse Landeros, Michael Vazquez, Junwon Kim, Layla Ghaffari, Jacqueline Gire O'Rourke, Daniel H. Geschwind, Mathew Blurton-Jones, David M. Holtzman, Rita Sattler, Robert H. Baloh
- English